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Gene: TRIML1 (tripartite motif family like 1) Pan paniscus

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Symbol:

TRIML1

Name:

tripartite motif family like 1

RGD ID:

11753967

Description:

ENCODES a protein that exhibits zinc ion binding (inferred); ASSOCIATED WITH autistic disorder (ortholog); factor XI deficiency (ortholog); Neurodevelopmental Disorders (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

probable E3 ubiquitin-protein ligase TRIML1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	185,859,683 - 185,870,381 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	186,214,255 - 186,224,957 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	180,294,211 - 180,302,527 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	192,483,186 - 192,491,414 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	192,483,189 - 192,491,414 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

factor XI deficiency (ISO)

Neurodevelopmental Disorders (ISO)

prostate cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

TRIML1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	185,859,683 - 185,870,381 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	186,214,255 - 186,224,957 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	180,294,211 - 180,302,527 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	192,483,186 - 192,491,414 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	192,483,189 - 192,491,414 (+)	Ensembl	panpan1.1		panPan2

TRIML1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	188,137,229 - 188,150,767 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	188,139,441 - 188,147,743 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	189,060,595 - 189,068,897 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	189,297,592 - 189,305,643 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	186,370,123 - 186,378,284 (+)	NCBI		Celera
Cytogenetic Map	4	q35.2	NCBI
HuRef	4	184,797,144 - 184,805,172 (+)	NCBI		HuRef
CHM1_1	4	189,037,036 - 189,045,104 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	191,484,912 - 191,498,442 (+)	NCBI		T2T-CHM13v2.0

Triml1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	43,582,843 - 43,633,531 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	43,582,844 - 43,594,523 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	43,129,806 - 43,180,494 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	43,129,807 - 43,141,486 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	44,215,161 - 44,226,840 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	44,628,624 - 44,640,303 (-)	NCBI		MGSCv36	mm8
Celera	8	45,810,994 - 45,822,269 (-)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	23.89	NCBI

Triml1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	55,727,383 - 55,737,770 (+)	NCBI		GRCr8
mRatBN7.2	16	48,994,968 - 49,005,343 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	48,997,252 - 49,005,417 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	16	52,169,426 - 52,177,548 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	52,169,450 - 52,177,586 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	51,895,696 - 51,903,792 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	52,328,994 - 52,336,646 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	52,329,068 - 52,336,721 (+)	NCBI
Celera	16	46,968,104 - 46,976,226 (+)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI

Triml1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	21,041,982 - 21,050,181 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	21,043,233 - 21,050,261 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRIML1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	42,954,353 - 42,984,128 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	42,954,012 - 42,980,309 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	43,442,909 - 43,472,680 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	45,174,211 - 45,204,062 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	45,173,861 - 45,180,528 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	43,134,589 - 43,142,611 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	43,714,818 - 43,744,586 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	43,844,318 - 43,874,160 (-)	NCBI		UU_Cfam_GSD_1.0

Triml1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	36,476,389 - 36,483,042 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936554	1,627,624 - 1,633,479 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936554	1,627,624 - 1,633,479 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIML1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	7,283,709 - 7,292,681 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	7,284,392 - 7,290,639 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TRIML1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	133,998,623 - 134,009,606 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	134,001,323 - 134,009,241 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	114,423,366 - 114,431,773 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Triml1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	19,097,452 - 19,102,862 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	19,095,899 - 19,103,190 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003823500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055112093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000050594 ⟹ ENSPPAP00000027751

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	4	192,483,189 - 192,491,414 (+)	Ensembl

RefSeq Acc Id:

XM_003823500 ⟹ XP_003823548

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	185,862,047 - 185,870,381 (+)	NCBI
NHGRI_mPanPan1	4	186,216,641 - 186,224,957 (+)	NCBI
Mhudiblu_PPA_v0	4	180,294,211 - 180,302,527 (+)	NCBI
PanPan1.1	4	192,483,186 - 192,491,414 (+)	NCBI

Sequence:

show sequence

GTCATAACAACATAGCAACAGGTCACCCGCGTGTTACTCAAAACTGTAGGACCACAGTGAGGGC
TTTGCTAATCCCAGAACAGAGGTGTAACCTGGCCGCATATCCAGCCTCGAGAAAATGTCTACAG
CAGATCTGATGGAGAACCTCAGGGAGGAACTCACCTGTTTCATCTGCTTAGACTATTTCAGCAG
CCCAGTGACCACCGAGTGTGGGCACAGCTTTTGTCTGGTGTGTCTCCTCAGGAGCTGGGAGGAA
CATAACACACCTTTATCTTGTCCTGAGTGCTGGAGGACCTTGGAGGGCCCGCATTTCCAGTCAA
ATGAGCGTCTGGGGAGGCTGGCCAGCATCGCCAGGCAGCTCCGGTCCCAGGTGCTGCAGAGCGA
GGATGAGCAGGGCAGCTACGGGAGGATGCCCACCACTGCCAAGGCGCTCTCCGATGACGAGCAG
GGTGGAAGCGCCTTCGTAGCCCAGAGCCACGGTGCAAACAGAGTGCATCTCTCCAGCGAGGCTG
AGGAGCATCACAGAGAGAAACTCCAGGAAATCCTGAATCTTTTGCGTGTAAGGAGAAAGGAAGC
TCAGGCTGTACTAACCCATGAGAAGGAGAGAGTGAAACTGTGCCAGGAAGAAACAAAGACTTGT
AAACAGGTTGTTGTGTCAGAATACATGAAAATGCACCAGTTCCTGAAGGAAGAGGAGCAGCTGC
AACTCCAGCTACTAGAACAGGAAGAGAGAGAGAACATGAGGAAGCTGAGGAACAATGAGATCAA
ACTGACCCAGCAAATCAGAAGCCTAAGCAAAATGATTGGGCAGATTGAGTCCTCAAGTCAAAGC
TCGGCTTTCGAATCTCTTGAGGAAGTGAGAGGAGCCCTGGAAAGGAGCGAGCCACTCTTGCTTC
AGTGTCCAGAGGCCACCACCACAGAGCTGAGTCTGTGCCGCATCACGGGAATGAAGGAGATGCT
AAGAAAATTCAGCACGGAGATAACGCTGGACCCAGCCACAGCTAATGCCTATCTCGTGTTGTCG
GAGGATCTGAAGAGTGTGAAATATGGGGGAAGCAGACAGCAGCTACCCGACAACCCGGAAAGAT
TTGACCAGTCTGCGACTGTGCTGGGTGCTCAGATCTTCACCAGTGGGAGACACTACTGGGAGGT
GGAGGTGGGAAACAAGACCGAGTGGGAAGTGGGCATCTGCAAGGACTCTGTGAGCAGAAAGGGG
AATCTCCCCAAGCCACCTGGGGACCTGTTCTCACTAATAGGTTTAAAAATCGGAGATGATTACA
GCCTCTGGGTCTCGTCACCTTTGAAAGGTCAGCACGTCAGAGAGCCTGTGTGTAAGGTTGGTGT
CTTCCTGGACTATGAATATGGACATGTAGCATTCTACAACGGGACGGATGAATCCCTCATCTAC
AGCTTCCCGCCGGCTTCTTTCCAAGAGGCCCTCAGGCCTATCTTTTCCCCCTGCCTCCCAAATG
AGGGGACAAACACAGACCCTCTCACCATCTGCTCACTGAATAGCCACGTCTGAGGGGCGTGCCC
TGAGCCGTCACAGCGGGCGATGTCTGAGACCAAGACATAACTATTAAGACGATGAAGGCATCGA
CAGTATTAATGTCAGGTGATCTGAAATAAACTCCCGTACCCCCACCCCACCCCCAAGAGTTTCC
ATTAACTTGATCCCATTATGAACAGCCACATTACACAATCAACTTCAACCCCAATAGAAGAGAG
CTGATCATATTCTGTGTCTTTGAGTAAATGTATTCTCTGGGCTACCCCATGTGTGTGCTGGTCA
CTCAAATATTGAGCCCCTATTACCATGAATCCTACTGCCATAGGTCAGATTTTATAAATATATG
TCACTTTTTCAAGTGTATTTAATTATTTGACTCT

hide sequence

RefSeq Acc Id:

XM_055112093 ⟹ XP_054968068

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	185,859,683 - 185,870,363 (+)	NCBI
NHGRI_mPanPan1	4	186,214,255 - 186,224,939 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003823548	(Get FASTA)	NCBI Sequence Viewer
	XP_054968068	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000027751.1

RefSeq Acc Id:	XP_003823548 ⟸ XM_003823500
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BHJ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPH FQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVHLS SEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYMKMHQFLKEE EQLQLQLLEQEERENMRKLRNNEIKLTQQIRSLSKMIGQIESSSQSSAFESLEEVRGALERSEP LLLQCPEATTTELSLCRITGMKEMLRKFSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDN PERFDQSATVLGAQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIG DDYSLWVSSPLKGQHVREPVCKVGVFLDYEYGHVAFYNGTDESLIYSFPPASFQEALRPIFSPC LPNEGTNTDPLTICSLNSHV hide sequence

Ensembl Acc Id:

ENSPPAP00000027751 ⟸ ENSPPAT00000050594

RefSeq Acc Id:	XP_054968068 ⟸ XM_055112093
- Peptide Label:	isoform X2

Protein Domains

B30.2/SPRY RING-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000036950	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000050594.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
InterPro	B30.2/SPRY	UniProtKB/TrEMBL
	B30.2/SPRY_sf	UniProtKB/TrEMBL
	Butyrophylin_SPRY	UniProtKB/TrEMBL
	ConA-like_dom_sf	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	SPRY_dom	UniProtKB/TrEMBL
	TRIM/RBCC	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	pps:100990873	UniProtKB/TrEMBL
NCBI Gene	TRIML1	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE TRIM	UniProtKB/TrEMBL
Pfam	PRY	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
	zf-C3HC4_4	UniProtKB/TrEMBL
PRINTS	BUTYPHLNCDUF	UniProtKB/TrEMBL
PROSITE	B302_SPRY	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	PRY	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF49899	UniProtKB/TrEMBL
UniProt	A0A2R9BHJ8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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