KLK14 (kallikrein related peptidase 14) - Rat Genome Database

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Gene: KLK14 (kallikrein related peptidase 14) Pan paniscus
Analyze
Symbol: KLK14
Name: kallikrein related peptidase 14
RGD ID: 11735981
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN fertilization (ortholog); negative regulation of G protein-coupled receptor signaling pathway (ortholog); positive regulation of G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); male infertility (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kallikrein-14
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,146,516 - 57,157,786 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,068,028 - 59,079,221 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,044,789 - 48,050,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,933,349 - 56,937,785 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,933,454 - 56,937,902 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KLK14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,146,516 - 57,157,786 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,068,028 - 59,079,221 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,044,789 - 48,050,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,933,349 - 56,937,785 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,933,454 - 56,937,902 (-)Ensemblpanpan1.1panPan2
KLK14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,077,494 - 51,084,210 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,077,495 - 51,084,245 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,580,751 - 51,587,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,272,966 - 56,279,314 (-)NCBINCBI36Build 36hg18NCBI36
Build 341956,272,385 - 56,279,314NCBI
Celera1948,633,233 - 48,639,581 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1947,914,209 - 47,920,557 (-)NCBIHuRef
CHM1_11951,583,150 - 51,589,500 (-)NCBICHM1_1
T2T-CHM13v2.01954,166,098 - 54,172,814 (-)NCBIT2T-CHM13v2.0
Klk14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,330,305 - 43,344,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,339,842 - 43,344,960 (+)EnsemblGRCm39 Ensembl
GRCm38743,680,880 - 43,695,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,690,418 - 43,695,536 (+)EnsemblGRCm38mm10GRCm38
MGSCv37750,945,789 - 50,950,389 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,558,461 - 43,563,061 (+)NCBIMGSCv36mm8
Celera739,154,573 - 39,159,175 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.26NCBI
Klk14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81103,258,327 - 103,273,792 (+)NCBIGRCr8
mRatBN7.2194,123,131 - 94,137,239 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl194,131,998 - 94,137,240 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0199,616,153 - 99,621,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,616,447 - 99,621,037 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01100,682,568 - 100,690,161 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,100,468 - 94,105,446 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1194,171,833 - 94,183,169 (+)NCBI
Celera188,400,688 - 88,405,960 (+)NCBICelera
Cytogenetic Map1q22NCBI
KLK14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,811,435 - 105,816,625 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1105,812,224 - 105,816,625 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,384,856 - 105,389,257 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,321,331 - 106,325,935 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,321,533 - 106,325,935 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,993,029 - 105,997,429 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,634,124 - 105,638,530 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,429,597 - 106,434,003 (+)NCBIUU_Cfam_GSD_1.0
Klk14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,838,923 - 22,843,484 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936889714,915 - 719,480 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936889714,933 - 719,305 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLK14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl655,719,729 - 55,725,458 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1655,719,698 - 55,726,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KLK14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1644,096,367 - 44,103,475 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl644,096,743 - 44,101,844 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607324,143,227 - 24,149,268 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_057300582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000063471   ⟹   ENSPPAP00000040554
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1956,933,454 - 56,937,902 (-)Ensembl
RefSeq Acc Id: XM_057300582   ⟹   XP_057156565
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22057,146,516 - 57,157,786 (-)NCBI
NHGRI_mPanPan11959,068,028 - 59,079,221 (-)NCBI
Protein Sequences
Protein RefSeqs XP_057156565 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040554.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000040554   ⟸   ENSPPAT00000063471
RefSeq Acc Id: XP_057156565   ⟸   XM_057300582
- UniProtKB: A0A2R9CF76 (UniProtKB/TrEMBL)
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042925 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063471.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene KLK14 ENTREZGENE
PANTHER KALLIKREIN-14 UniProtKB/TrEMBL
  KALLIKREIN-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A2R9CF76 ENTREZGENE, UniProtKB/TrEMBL