NIBAN2 (niban apoptosis regulator 2) - Rat Genome Database

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Gene: NIBAN2 (niban apoptosis regulator 2) Pan paniscus
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Symbol: NIBAN2
Name: niban apoptosis regulator 2
RGD ID: 11733173
Description: ENCODES a protein that exhibits transcription coactivator activity (inferred); INVOLVED IN gonadotropin secretion (inferred); negative regulation of apoptotic process (inferred); negative regulation of cell population proliferation (inferred); ASSOCIATED WITH congenital disorder of glycosylation Iu (ortholog); COVID-19 (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM129B; family with sequence similarity 129 member B; niban-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,784,223 - 11,849,159 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,787,847 - 11,851,506 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,625,411 - 98,689,077 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,299,475 - 127,362,552 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,299,475 - 127,371,459 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
adherens junction  (IEA)
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA,ISO)
plasma membrane  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
NIBAN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,784,223 - 11,849,159 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,787,847 - 11,851,506 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,625,411 - 98,689,077 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,299,475 - 127,362,552 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,299,475 - 127,371,459 (-)Ensemblpanpan1.1panPan2
NIBAN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,505,343 - 127,579,031 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,505,339 - 127,578,989 (-)EnsemblGRCh38hg38GRCh38
GRCh379130,267,622 - 130,341,310 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,307,439 - 129,381,089 (-)NCBINCBI36Build 36hg18NCBI36
Build 349127,347,172 - 127,410,909NCBI
Celera9100,918,505 - 100,992,132 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef999,883,553 - 99,957,416 (-)NCBIHuRef
CHM1_19130,418,921 - 130,492,461 (-)NCBICHM1_1
T2T-CHM13v2.09139,712,305 - 139,786,022 (-)NCBIT2T-CHM13v2.0
Niban2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,766,146 - 32,815,265 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,766,126 - 32,815,266 (+)EnsemblGRCm39 Ensembl
GRCm38232,876,134 - 32,925,253 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,876,114 - 32,925,254 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,731,654 - 32,780,773 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,698,234 - 32,747,258 (+)NCBIMGSCv36mm8
Celera232,583,095 - 32,632,235 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Niban2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,572,356 - 36,621,968 (+)NCBIGRCr8
mRatBN7.2316,174,674 - 16,224,293 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,174,659 - 16,224,293 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx319,242,343 - 19,292,066 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,827,347 - 27,877,070 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0326,079,098 - 26,128,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,921,715 - 11,971,327 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,921,715 - 11,971,327 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,257,993 - 17,307,290 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,862,604 - 11,912,117 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,759,166 - 11,808,481 (+)NCBI
Celera310,914,173 - 10,963,784 (+)NCBICelera
Cytogenetic Map3p11NCBI
Niban2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554191,072,243 - 1,119,620 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554191,089,602 - 1,119,620 (+)NCBIChiLan1.0ChiLan1.0
NIBAN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,802,010 - 55,853,960 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,802,014 - 55,852,540 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,994,587 - 55,046,576 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,723,425 - 56,775,654 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,723,409 - 56,775,654 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,483,586 - 55,535,366 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,798,215 - 55,850,400 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,889,577 - 55,941,107 (+)NCBIUU_Cfam_GSD_1.0
Niban2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,452,680 - 195,500,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,221,241 - 15,269,521 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,221,207 - 15,269,515 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NIBAN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,010,297 - 268,065,930 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,010,297 - 268,066,022 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21301,920,994 - 301,974,856 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NIBAN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,556,661 - 10,621,281 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,556,650 - 10,621,589 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,595,833 - 5,661,162 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Niban2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,951,934 - 7,996,256 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,951,943 - 7,996,260 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000042086   ⟹   ENSPPAP00000019327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9127,299,475 - 127,362,552 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000042089   ⟹   ENSPPAP00000019330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9127,301,008 - 127,371,459 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000042090   ⟹   ENSPPAP00000019331
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9127,301,008 - 127,329,091 (-)Ensembl
RefSeq Acc Id: XM_003822289   ⟹   XP_003822337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,785,500 - 11,849,159 (+)NCBI
NHGRI_mPanPan1911,787,847 - 11,851,506 (+)NCBI
Mhudiblu_PPA_v0998,625,411 - 98,689,077 (-)NCBI
PanPan1.19127,299,475 - 127,362,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063594192   ⟹   XP_063450262
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,784,223 - 11,849,159 (+)NCBI
RefSeq Acc Id: XM_063594193   ⟹   XP_063450263
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,786,612 - 11,849,159 (+)NCBI
RefSeq Acc Id: XM_063594194   ⟹   XP_063450264
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,792,921 - 11,849,159 (+)NCBI
RefSeq Acc Id: XP_003822337   ⟸   XM_003822289
- Peptide Label: isoform X1
- UniProtKB: A0A2R9APM5 (UniProtKB/TrEMBL),   A0A2R9AU87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000019327   ⟸   ENSPPAT00000042086
Ensembl Acc Id: ENSPPAP00000019330   ⟸   ENSPPAT00000042089
Ensembl Acc Id: ENSPPAP00000019331   ⟸   ENSPPAT00000042090
RefSeq Acc Id: XP_063450262   ⟸   XM_063594192
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063450263   ⟸   XM_063594193
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063450264   ⟸   XM_063594194
- Peptide Label: isoform X3
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042086.1 UniProtKB/TrEMBL
  ENSPPAT00000042089.1 UniProtKB/TrEMBL
  ENSPPAT00000042090.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro Niban-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report pps:100989046 UniProtKB/TrEMBL
NCBI Gene FAM129B ENTREZGENE
PANTHER PROTEIN NIBAN 2 UniProtKB/TrEMBL
  PTHR14392 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A2R9APM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9APN2_PANPA UniProtKB/TrEMBL
  A0A2R9AU87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-23 NIBAN2  niban apoptosis regulator 2  FAM129B  family with sequence similarity 129 member B  Symbol and/or name change 5135510 APPROVED