TMEM14A (transmembrane protein 14A)

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Gene: TMEM14A (transmembrane protein 14A) Pan paniscus

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Symbol:

TMEM14A

Name:

transmembrane protein 14A

RGD ID:

11713699

Description:

INVOLVED IN negative regulation of apoptotic process (inferred); negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (inferred); regulation of heme biosynthetic process (inferred); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); mitochondrial membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	67,135,737 - 67,157,973 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	63,018,973 - 63,034,401 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	52,226,416 - 52,241,846 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	53,492,943 - 53,508,340 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	53,492,943 - 53,508,340 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of apoptotic process (IEA)

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (IEA)

regulation of heme biosynthetic process (IEA)

Cellular Component

endoplasmic reticulum membrane (IEA)

membrane (IEA)

mitochondrial membrane (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

TMEM14A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	67,135,737 - 67,157,973 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	63,018,973 - 63,034,401 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	52,226,416 - 52,241,846 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	53,492,943 - 53,508,340 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	53,492,943 - 53,508,340 (+)	Ensembl	panpan1.1		panPan2

TMEM14A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	52,671,113 - 52,686,588 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	52,671,113 - 52,686,588 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	52,535,911 - 52,551,386 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	52,643,843 - 52,659,345 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	52,643,863 - 52,659,342	NCBI
Celera	6	54,196,977 - 54,212,463 (+)	NCBI		Celera
Cytogenetic Map	6	p12.2	NCBI
HuRef	6	52,367,119 - 52,382,535 (+)	NCBI		HuRef
CHM1_1	6	52,538,093 - 52,553,590 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	52,509,853 - 52,525,372 (+)	NCBI		T2T-CHM13v2.0

Tmem14a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	21,236,609 - 21,300,391 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	21,288,799 - 21,300,391 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	21,166,436 - 21,230,167 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	21,218,575 - 21,230,167 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	21,208,712 - 21,220,248 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	21,203,813 - 21,215,315 (+)	NCBI		MGSCv36	mm8
Celera	1	21,087,828 - 21,099,400 (+)	NCBI		Celera
Cytogenetic Map	1	A4	NCBI
cM Map	1	6.5	NCBI

Tmem14a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	31,137,011 - 31,148,794 (+)	NCBI		GRCr8
mRatBN7.2	9	23,640,594 - 23,652,379 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	23,640,594 - 23,652,379 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	9	23,733,039 - 23,734,463 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	32,131,886 - 32,145,560 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	37,252,577 - 37,266,255 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	35,567,818 - 35,581,496 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	27,333,956 - 27,345,612 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,333,956 - 27,351,295 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	9	27,343,853 - 27,345,070 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	26,187,241 - 26,198,598 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	19,986,826 - 19,999,299 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	19,984,156 - 19,996,628 (+)	NCBI
Celera	9	21,214,591 - 21,228,190 (+)	NCBI		Celera
Cytogenetic Map	9	q13	NCBI

Tmem14a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	5,373,251 - 5,379,767 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955411	5,372,713 - 5,380,033 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM14A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	20,303,724 - 20,318,336 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	20,198,868 - 20,213,473 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	20,801,318 - 20,815,838 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	12	20,307,098 - 20,321,683 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	20,410,701 - 20,425,306 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	20,549,342 - 20,563,953 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem14a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	55,761,976 - 55,780,517 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	8,180,141 - 8,185,884 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	8,179,949 - 8,198,204 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM14A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	46,509,777 - 46,517,732 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	46,509,724 - 46,517,735 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	134,211,575 - 134,218,991 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM14A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	19,819,918 - 19,835,919 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	19,820,458 - 19,829,781 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	52,574,544 - 52,590,827 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem14a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624855	3,388,847 - 3,394,990 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624855	3,388,292 - 3,411,943 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_063605313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000047200 ⟹ ENSPPAP00000024375

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	6	53,492,943 - 53,508,340 (+)	Ensembl

RefSeq Acc Id:

XM_063605313 ⟹ XP_063461383

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	5	67,135,737 - 67,157,973 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_063461383	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000024375.1

Ensembl Acc Id:

ENSPPAP00000024375 ⟸ ENSPPAT00000047200

RefSeq Acc Id:	XP_063461383 ⟸ XM_063605313
- UniProtKB:	A0A2R9B801 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000035341	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000047200.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.1740	UniProtKB/TrEMBL
	6.10.250.1330	UniProtKB/TrEMBL
InterPro	TMEM14	UniProtKB/TrEMBL
	TMEM14_sf	UniProtKB/TrEMBL
KEGG Report	pps:100976677	UniProtKB/TrEMBL
NCBI Gene	TMEM14A	ENTREZGENE
PANTHER	PTHR12668	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 14A	UniProtKB/TrEMBL
Pfam	Tmemb_14	UniProtKB/TrEMBL
UniProt	A0A2R9B801	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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