PWWP2B (PWWP domain containing 2B) - Rat Genome Database

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Gene: PWWP2B (PWWP domain containing 2B) Pan paniscus
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Symbol: PWWP2B
Name: PWWP domain containing 2B
RGD ID: 11695792
Description: ENCODES a protein that exhibits NuRD complex binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of transcription elongation by RNA polymerase II (inferred); regulation of cold-induced thermogenesis (inferred); ASSOCIATED WITH distal 10q deletion syndrome (ortholog); polycystic ovary syndrome (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PWWP domain-containing protein 2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBINHGRI_mPanPan1
PanPan1.110133,295,329 - 133,315,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10133,295,325 - 133,315,575 (+)Ensemblpanpan1.1panPan2


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PWWP2BBonobodistal 10q deletion syndrome  ISOPWWP2B (Homo sapiens)8554872ClinVar Annotator: match by term: Distal 10q deletion syndromeClinVarPMID:31690835
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PWWP2BBonobopolycystic ovary syndrome  ISOPWWP2B (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21411543


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PWWP2BBonobochromatin remodeling involved_inIEAUniProtKB:E9Q9M8 and ensembl:ENSMUSP00000130888150520179 EnsemblGO_REF:0000107
PWWP2BBonobopositive regulation of transcription elongation by RNA polymerase II involved_inIEAUniProtKB:E9Q9M8 and ensembl:ENSMUSP00000130888150520179 EnsemblGO_REF:0000107
PWWP2BBonoboregulation of cold-induced thermogenesis involved_inIEAUniProtKB:E9Q9M8 and ensembl:ENSMUSP00000130888150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PWWP2BBonobonucleoplasm located_inIEAPANTHER:PTN002747439150520179 TreeGrafterGO_REF:0000118
PWWP2BBonobonucleoplasm located_inIEAUniProtKB:Q6NUJ5 and ensembl:ENSP00000306324150520179 EnsemblGO_REF:0000107
PWWP2BBonobonucleus located_inIEAUniProtKB:E9Q9M8 and ensembl:ENSMUSP00000130888150520179 EnsemblGO_REF:0000107
PWWP2BBonobonucleus located_inIEAPANTHER:PTN002747439150520179 TreeGrafterGO_REF:0000118

Molecular Function

  

PMID:30032202  



PWWP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBINHGRI_mPanPan1
PanPan1.110133,295,329 - 133,315,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10133,295,325 - 133,315,575 (+)Ensemblpanpan1.1panPan2
PWWP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810132,397,200 - 132,417,859 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10132,397,168 - 132,417,859 (+)EnsemblGRCh38hg38GRCh38
GRCh3710134,210,704 - 134,231,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610134,060,692 - 134,081,353 (+)NCBINCBI36Build 36hg18NCBI36
Celera10128,008,481 - 128,021,704 (-)NCBICelera
Cytogenetic Map10q26.3NCBI
HuRef10127,770,083 - 127,783,306 (+)NCBIHuRef
CHM1_110134,492,562 - 134,513,250 (+)NCBICHM1_1
T2T-CHM13v2.010133,344,759 - 133,365,447 (+)NCBIT2T-CHM13v2.0
Pwwp2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397138,828,398 - 138,847,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7138,828,398 - 138,849,819 (+)EnsemblGRCm39 Ensembl
GRCm387139,248,482 - 139,267,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7139,248,482 - 139,269,903 (+)EnsemblGRCm38mm10GRCm38
MGSCv377146,434,381 - 146,453,152 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367139,099,802 - 139,118,573 (+)NCBIMGSCv36mm8
Celera7139,041,967 - 139,060,753 (+)NCBICelera
Cytogenetic Map7F4NCBI
cM Map784.39NCBI
Pwwp2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81203,470,172 - 203,489,575 (+)NCBIGRCr8
mRatBN7.21194,040,395 - 194,059,979 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1194,041,341 - 194,059,958 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1202,411,608 - 202,430,266 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01209,546,149 - 209,564,799 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01202,219,911 - 202,238,561 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01211,579,706 - 211,600,715 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,582,077 - 211,600,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,503,779 - 218,524,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41199,023,641 - 199,042,279 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11199,173,642 - 199,191,671 (+)NCBI
Celera1191,730,045 - 191,748,683 (+)NCBICelera
Cytogenetic Map1q41NCBI
Pwwp2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547710,017,443 - 10,039,675 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547710,017,449 - 10,039,691 (+)NCBIChiLan1.0ChiLan1.0
PWWP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12840,327,255 - 40,330,711 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2840,381,861 - 40,403,664 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02840,961,589 - 40,983,405 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2840,961,592 - 40,977,588 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12840,445,328 - 40,467,113 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02840,435,497 - 40,457,305 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02840,837,209 - 40,859,024 (+)NCBIUU_Cfam_GSD_1.0
Pwwp2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244072136,804,071 - 6,816,522 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648618,745,150 - 18,746,814 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648618,744,434 - 18,757,227 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PWWP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14140,636,964 - 140,657,623 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114140,635,806 - 140,657,675 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214152,508,852 - 152,524,670 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PWWP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19124,984,851 - 125,012,202 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9124,988,407 - 124,997,532 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604886,474,674 - 86,502,123 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pwwp2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473714,419,670 - 14,442,933 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473714,420,293 - 14,442,969 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000037754   ⟹   ENSPPAP00000015066
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10133,295,325 - 133,315,575 (+)Ensembl
RefSeq Acc Id: XM_034951481   ⟹   XP_034807372
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBI
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBI
RefSeq Acc Id: XR_004669325
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBI
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBI
RefSeq Acc Id: XR_010113221
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28144,388,562 - 144,409,772 (+)NCBI
Protein RefSeqs XP_034807372 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000015066.1
Ensembl Acc Id: ENSPPAP00000015066   ⟸   ENSPPAT00000037754
RefSeq Acc Id: XP_034807372   ⟸   XM_034951481
- UniProtKB: A0A2R9ADQ3 (UniProtKB/TrEMBL)
PWWP



1 to 12 of 12 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000030691 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000037754.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
InterPro PWWP_dom UniProtKB/TrEMBL
NCBI Gene PWWP2B ENTREZGENE
PANTHER DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED UniProtKB/TrEMBL
  PWWP DOMAIN-CONTAINING PROTEIN 2B UniProtKB/TrEMBL
Pfam PWWP UniProtKB/TrEMBL
PROSITE PWWP UniProtKB/TrEMBL
SMART PWWP UniProtKB/TrEMBL
Superfamily-SCOP Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0A2R9ADQ3 ENTREZGENE, UniProtKB/TrEMBL
1 to 12 of 12 rows