PWWP2B (PWWP domain containing 2B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: PWWP2B (PWWP domain containing 2B) Pan paniscus
Analyze
Symbol: PWWP2B
Name: PWWP domain containing 2B
RGD ID: 11695792
Description: ENCODES a protein that exhibits NuRD complex binding (inferred); INVOLVED IN chromatin remodeling (inferred); positive regulation of transcription elongation by RNA polymerase II (inferred); regulation of cold-induced thermogenesis (inferred); ASSOCIATED WITH distal 10q deletion syndrome (ortholog); polycystic ovary syndrome (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PWWP domain-containing protein 2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBINHGRI_mPanPan1
PanPan1.110133,295,329 - 133,315,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10133,295,325 - 133,315,575 (+)Ensemblpanpan1.1panPan2


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PWWP2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBINHGRI_mPanPan1
PanPan1.110133,295,329 - 133,315,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10133,295,325 - 133,315,575 (+)Ensemblpanpan1.1panPan2
PWWP2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810132,397,200 - 132,417,859 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10132,397,168 - 132,417,859 (+)EnsemblGRCh38hg38GRCh38
GRCh3710134,210,704 - 134,231,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610134,060,692 - 134,081,353 (+)NCBINCBI36Build 36hg18NCBI36
Celera10128,008,481 - 128,021,704 (-)NCBICelera
Cytogenetic Map10q26.3NCBI
HuRef10127,770,083 - 127,783,306 (+)NCBIHuRef
CHM1_110134,492,562 - 134,513,250 (+)NCBICHM1_1
T2T-CHM13v2.010133,344,759 - 133,365,447 (+)NCBIT2T-CHM13v2.0
Pwwp2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397138,828,398 - 138,847,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7138,828,398 - 138,849,819 (+)EnsemblGRCm39 Ensembl
GRCm387139,248,482 - 139,267,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7139,248,482 - 139,269,903 (+)EnsemblGRCm38mm10GRCm38
MGSCv377146,434,381 - 146,453,152 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367139,099,802 - 139,118,573 (+)NCBIMGSCv36mm8
Celera7139,041,967 - 139,060,753 (+)NCBICelera
Cytogenetic Map7F4NCBI
cM Map784.39NCBI
Pwwp2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81203,470,172 - 203,489,575 (+)NCBIGRCr8
mRatBN7.21194,040,395 - 194,059,979 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1194,041,341 - 194,059,958 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1202,411,608 - 202,430,266 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01209,546,149 - 209,564,799 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01202,219,911 - 202,238,561 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01211,579,706 - 211,600,715 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,582,077 - 211,600,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,503,779 - 218,524,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41199,023,641 - 199,042,279 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11199,173,642 - 199,191,671 (+)NCBI
Celera1191,730,045 - 191,748,683 (+)NCBICelera
Cytogenetic Map1q41NCBI
Pwwp2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547710,017,443 - 10,039,675 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547710,017,449 - 10,039,691 (+)NCBIChiLan1.0ChiLan1.0
PWWP2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12840,327,255 - 40,330,711 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2840,381,861 - 40,403,664 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02840,961,589 - 40,983,405 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2840,961,592 - 40,977,588 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12840,445,328 - 40,467,113 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02840,435,497 - 40,457,305 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02840,837,209 - 40,859,024 (+)NCBIUU_Cfam_GSD_1.0
Pwwp2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244072136,804,071 - 6,816,522 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648618,745,150 - 18,746,814 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648618,744,434 - 18,757,227 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PWWP2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14140,636,964 - 140,657,623 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114140,635,806 - 140,657,675 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214152,508,852 - 152,524,670 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PWWP2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19124,984,851 - 125,012,202 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9124,988,407 - 124,997,532 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604886,474,674 - 86,502,123 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pwwp2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473714,419,670 - 14,442,933 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473714,420,293 - 14,442,969 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000037754   ⟹   ENSPPAP00000015066
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10133,295,325 - 133,315,575 (+)Ensembl
RefSeq Acc Id: XM_034951481   ⟹   XP_034807372
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBI
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBI
RefSeq Acc Id: XR_004669325
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28144,388,541 - 144,409,772 (+)NCBI
NHGRI_mPanPan110144,393,914 - 144,415,129 (+)NCBI
RefSeq Acc Id: XR_010113221
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28144,388,562 - 144,409,772 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034807372 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000015066.1
Ensembl Acc Id: ENSPPAP00000015066   ⟸   ENSPPAT00000037754
RefSeq Acc Id: XP_034807372   ⟸   XM_034951481
- UniProtKB: A0A2R9ADQ3 (UniProtKB/TrEMBL)
Protein Domains
PWWP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030691 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000037754.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
InterPro PWWP_dom UniProtKB/TrEMBL
NCBI Gene PWWP2B ENTREZGENE
PANTHER DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED UniProtKB/TrEMBL
  PWWP DOMAIN-CONTAINING PROTEIN 2B UniProtKB/TrEMBL
Pfam PWWP UniProtKB/TrEMBL
PROSITE PWWP UniProtKB/TrEMBL
SMART PWWP UniProtKB/TrEMBL
Superfamily-SCOP Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0A2R9ADQ3 ENTREZGENE, UniProtKB/TrEMBL