EPHB6 (EPH receptor B6) - Rat Genome Database

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Gene: EPHB6 (EPH receptor B6) Pan paniscus
Analyze
Symbol: EPHB6
Name: EPH receptor B6
RGD ID: 11690001
Description: ENCODES a protein that exhibits ATP binding (inferred); ephrin receptor activity (inferred); transmembrane-ephrin receptor activity (inferred); INVOLVED IN activated T cell proliferation (ortholog); positive regulation of T cell costimulation (ortholog); T cell mediated immunity (ortholog); ASSOCIATED WITH Hereditary Pancreatitis (ortholog); malaria (ortholog); myoepithelioma (ortholog); FOUND IN cell surface (inferred); dendrite (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ephrin type-B receptor 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1731,713,585 - 31,729,765 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07134,845,936 - 134,862,114 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17147,337,558 - 147,353,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7147,337,558 - 147,353,575 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EPHB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1731,713,585 - 31,729,765 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07134,845,936 - 134,862,114 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17147,337,558 - 147,353,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7147,337,558 - 147,353,575 (+)Ensemblpanpan1.1panPan2
EPHB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,855,076 - 142,871,093 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7142,855,061 - 142,871,094 (+)EnsemblGRCh38hg38GRCh38
GRCh377142,552,838 - 142,568,847 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,262,914 - 142,278,969 (+)NCBINCBI36Build 36hg18NCBI36
Build 347142,069,628 - 142,085,682NCBI
Celera7137,390,094 - 137,406,149 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,891,079 - 136,907,058 (+)NCBIHuRef
CHM1_17142,488,986 - 142,505,065 (+)NCBICHM1_1
T2T-CHM13v2.07144,210,901 - 144,226,909 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27141,954,640 - 141,970,711 (+)NCBI
Ephb6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39641,581,940 - 41,597,445 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl641,582,416 - 41,597,443 (+)EnsemblGRCm39 Ensembl
GRCm38641,603,834 - 41,620,509 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl641,605,482 - 41,620,509 (+)EnsemblGRCm38mm10GRCm38
MGSCv37641,555,481 - 41,570,506 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36641,535,175 - 41,550,109 (+)NCBIMGSCv36mm8
Celera641,558,073 - 41,573,098 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map619.77NCBI
Ephb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8471,458,632 - 71,473,889 (+)NCBIGRCr8
mRatBN7.2470,491,973 - 70,507,230 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl470,491,973 - 70,507,230 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx475,409,463 - 75,424,754 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0471,322,717 - 71,338,007 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0469,731,061 - 69,746,342 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0470,903,253 - 70,918,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl470,903,253 - 70,918,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,690,323 - 135,705,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,316,600 - 69,331,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1469,593,119 - 69,607,982 (+)NCBI
Celera465,457,027 - 65,472,281 (+)NCBICelera
Cytogenetic Map4q23NCBI
Ephb6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955494812,855 - 820,475 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955494812,482 - 820,679 (+)NCBIChiLan1.0ChiLan1.0
EPHB6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,706,302 - 6,718,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,706,313 - 6,718,566 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0166,617,379 - 6,632,929 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,617,386 - 6,629,133 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,570,657 - 6,586,203 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,422,134 - 6,437,682 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,480,896 - 6,496,448 (-)NCBIUU_Cfam_GSD_1.0
Ephb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511812,558,265 - 12,573,314 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936527329,990 - 345,167 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936527330,034 - 345,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHB6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,346,565 - 7,389,504 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,346,793 - 7,419,859 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,652,270 - 7,659,953 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121111,742,236 - 111,750,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21111,742,268 - 111,752,179 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660728,457,010 - 8,474,045 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ephb6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480012,069,908 - 12,074,669 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480012,069,977 - 12,076,992 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000042056   ⟹   ENSPPAP00000019298
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7147,337,558 - 147,353,575 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000042060   ⟹   ENSPPAP00000019302
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7147,345,709 - 147,347,101 (+)Ensembl
RefSeq Acc Id: XM_003820560   ⟹   XP_003820608
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBI
NHGRI_mPanPan1731,713,586 - 31,729,765 (+)NCBI
Mhudiblu_PPA_v07134,845,937 - 134,862,114 (+)NCBI
PanPan1.17147,337,558 - 147,353,575 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008974008   ⟹   XP_008972256
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBI
NHGRI_mPanPan1731,713,586 - 31,729,765 (+)NCBI
Mhudiblu_PPA_v07134,845,937 - 134,862,114 (+)NCBI
PanPan1.17147,337,558 - 147,353,575 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014345845   ⟹   XP_014201331
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBI
NHGRI_mPanPan1731,713,586 - 31,729,765 (+)NCBI
Mhudiblu_PPA_v07134,845,937 - 134,862,114 (+)NCBI
PanPan1.17147,337,558 - 147,353,575 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014345846   ⟹   XP_014201332
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBI
NHGRI_mPanPan1731,713,585 - 31,729,765 (+)NCBI
Mhudiblu_PPA_v07134,845,936 - 134,862,114 (+)NCBI
PanPan1.17147,337,558 - 147,353,575 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034965122   ⟹   XP_034821013
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBI
NHGRI_mPanPan1731,713,586 - 31,729,765 (+)NCBI
Mhudiblu_PPA_v07134,845,937 - 134,862,114 (+)NCBI
RefSeq Acc Id: XM_063606398   ⟹   XP_063462468
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26179,709,362 - 179,719,509 (+)NCBI
RefSeq Acc Id: XP_014201331   ⟸   XM_014345845
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AQ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014201332   ⟸   XM_014345846
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AQ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003820608   ⟸   XM_003820560
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AQ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008972256   ⟸   XM_008974008
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AQ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034821013   ⟸   XM_034965122
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AQ56 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000019302   ⟸   ENSPPAT00000042060
Ensembl Acc Id: ENSPPAP00000019298   ⟸   ENSPPAT00000042056
RefSeq Acc Id: XP_063462468   ⟸   XM_063606398
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AQ56 (UniProtKB/TrEMBL)
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032825 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042056.1 UniProtKB/TrEMBL
  ENSPPAT00000042060.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ephrin a2 ectodomain UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/TrEMBL
InterPro Eph_TM UniProtKB/TrEMBL
  Ephrin_rcpt_lig-bd_dom UniProtKB/TrEMBL
  Ephrin_rcpt_TKs UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr-kin_ephrin_A/B_rcpt-like UniProtKB/TrEMBL
  Tyr_kinase_ephrin_rcpt UniProtKB/TrEMBL
  Tyr_kinase_rcpt_V_CS UniProtKB/TrEMBL
KEGG Report pps:100990739 UniProtKB/TrEMBL
NCBI Gene EPHB6 ENTREZGENE
PANTHER EPH RECEPTOR A5 UniProtKB/TrEMBL
  EPHRIN TYPE-B RECEPTOR 6 UniProtKB/TrEMBL
Pfam EphA2_TM UniProtKB/TrEMBL
  Ephrin_lbd UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
PIRSF TyrPK_ephrin_receptor UniProtKB/TrEMBL
PRINTS FNTYPEIII UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE EPH_LBD UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_1 UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_2 UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART EPH_lbd UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A2R9APK2_PANPA UniProtKB/TrEMBL
  A0A2R9AQ56 ENTREZGENE, UniProtKB/TrEMBL