CVCL_X582 - Rat Genome Database

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Cell Line : CVCL_X582 (THP1-Xblue) Homo sapiens

Symbol: CVCL_X582
Name: THP1-Xblue
RGD ID: 21186412
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Gender: Male
Characteristics: Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a NF-KappaB/AP-1 promoter
Genomic Alteration: Sequence variation: Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line); Sequence variation: Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line); Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line); Transfected with: HGNC; 439; ALPP
Related Genes: ALPP  
Derived From Cell Lines: CVCL_0006 (THP-1)
Child Cell Lines: CVCL_X583 (THP1-Xblue-CD14)
CVCL_X584 (THP1-Xblue-MD2-CD14)
CVCL_X586 (THP1-XBlue-defMyD)

References
Additional References at PubMed
PMID:25130606  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_X582 CELLOSAURUS
Cellosaurus CVCL_X582 CELLOSAURUS
NCIt C9163 CELLOSAURUS
Orphanet 514 CELLOSAURUS
Wikidata Q54972375 CELLOSAURUS