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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351854
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL11
Name: C-C motif chemokine ligand 11
Acc ID: CHEBI:9753
Term: troglitazone
Definition: A chromane that has formula C24H27NO5S.
Chemical ID: MESH:C057693
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL11decreases activityEXP 6480464CTDtroglitazone results in decreased activity of CCL11 proteinPMID:12644321
CCL11multiple interactionsEXP 6480464CTDPPARA protein affects the reaction [troglitazone inhibits the reaction [TNF protein results in increased expression of CCL11 protein]]; troglitazone inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; troglitazone inhibits the reaction [TNF protein results in increased expression of CCL11 protein]PMID:15531761
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