GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CXCL12 | decreases expression | EXP | | 6480464 | CTD | Raloxifene Hydrochloride results in decreased expression of CXCL12 mRNA | PMID:26865669 | CXCL12 | multiple interactions | EXP | | 6480464 | CTD | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein] | PMID:19059307 PMID:20549624 PMID:21185374 | |
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