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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322050
Species: Homo sapiens
RGD Object: Gene
Symbol: MAD2L1
Name: mitotic arrest deficient 2 like 1
Acc ID: CHEBI:8461
Term: promethazine
Definition: A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Chemical ID: MESH:D011398
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAD2L1decreases expressionISOMad2l1 (Rattus norvegicus)6480464CTDPromethazine results in decreased expression of MAD2L1 mRNAPMID:26011634
MAD2L1increases expressionISOMad2l1 (Rattus norvegicus)6480464CTDPromethazine results in increased expression of MAD2L1 mRNAPMID:26558467
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