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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14209343
Species: Sus scrofa
RGD Object: Gene
Symbol: IL1A
Name: interleukin 1 alpha
Acc ID: CHEBI:7599
Term: Nivalenol
Definition: A trichothecene that has formula C15H20O7.
Chemical ID: MESH:C038405
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1Adecreases expressionEXP 6480464CTDnivalenol results in decreased expression of IL1A mRNAPMID:23688591
IL1Aincreases expressionEXP 6480464CTDnivalenol results in increased expression of IL1A mRNAPMID:23688591 PMID:27915442
IL1Amultiple interactionsEXP 6480464CTD[deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA; [nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA]; nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]PMID:23688591 PMID:27915442
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