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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345686
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL8
Name: C-X-C motif chemokine ligand 8
Acc ID: CHEBI:75095
Term: chrysin
Definition: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.
Chemical ID: MESH:C043561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL8increases expressionEXP 6480464CTDchrysin results in increased expression of CXCL8 mRNAPMID:18457675
CXCL8multiple interactionsEXP 6480464CTDchrysin inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]PMID:18377686
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