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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314829
Species: Mus musculus
RGD Object: Gene
Symbol: Trdmt1
Name: tRNA aspartic acid methyltransferase 1
Acc ID: CHEBI:6437
Term: levetiracetam
Definition: A pyrrolidinone and carboxamide that is N-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the S enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine.
Chemical ID: MESH:D000077287
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trdmt1decreases expressionISOTrdmt1 (Rattus norvegicus)6480464CTDLevetiracetam results in decreased expression of TRDMT1 mRNAPMID:20345932
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