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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736487
Species: Mus musculus
RGD Object: Gene
Symbol: Slco2b1
Name: solute carrier organic anion transporter family, member 2b1
Acc ID: CHEBI:63609
Term: mefloquine
Definition: A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown.
Chemical ID: MESH:D015767
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slco2b1multiple interactionsISOSLCO2B1 (Homo sapiens)6480464CTDMefloquine affects the reaction [SLCO2B1 protein results in increased uptake of estrone sulfate]PMID:27504015
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