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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589127
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Upf1
Name: UPF1, RNA helicase and ATPase
Acc ID: CHEBI:529996
Term: cytochalasin D
Definition: An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis.
Chemical ID: MESH:D015638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Upf1affects localizationISOUPF1 (Homo sapiens)6480464CTDCytochalasin D affects the localization of UPF1 proteinPMID:28743738
Upf1multiple interactionsISOUPF1 (Homo sapiens)6480464CTDCytochalasin D inhibits the reaction [UPF1 protein binds to ACTG1 protein]PMID:28743738
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