Upf1 (UPF1, RNA helicase and ATPase) - Rat Genome Database

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Gene: Upf1 (UPF1, RNA helicase and ATPase) Rattus norvegicus
Analyze
Symbol: Upf1
Name: UPF1, RNA helicase and ATPase
RGD ID: 1589127
Description: Predicted to enable several functions, including ATP hydrolysis activity; helicase activity; and nucleic acid binding activity. Predicted to be involved in several processes, including chromosome organization; regulation of gene expression; and regulation of telomere maintenance. Predicted to act upstream of or within positive regulation of mRNA cis splicing, via spliceosome. Predicted to be located in chromosome; cytosol; and nucleoplasm. Predicted to be part of exon-exon junction complex and supraspliceosomal complex. Predicted to be active in cytoplasm. Orthologous to human UPF1 (UPF1 RNA helicase and ATPase); INTERACTS WITH acrylamide; bisphenol A; thioacetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC684558; regulator of nonsense transcripts 1; similar to regulator of nonsense transcripts 1; UPF1 regulator of nonsense transcripts homolog; UPF1 regulator of nonsense transcripts homolog (yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,110,531 - 19,131,327 (+)NCBIGRCr8
mRatBN7.21619,076,594 - 19,097,365 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,076,322 - 19,096,568 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01620,824,888 - 20,845,632 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,824,864 - 20,845,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,677,403 - 20,698,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1619,266,888 - 19,287,629 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
amlexanox  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camptothecin  (ISO)
carmustine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
cytochalasin D  (ISO)
DDE  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
geneticin  (ISO)
ivermectin  (ISO)
jaspamide  (ISO)
L-methionine  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
ozone  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
torcetrapib  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9231034   PMID:9620853   PMID:12554878   PMID:16086026   PMID:16488880   PMID:16601204   PMID:16789828   PMID:17468741   PMID:17916692   PMID:18362360   PMID:18369367   PMID:21419344  
PMID:21700703   PMID:21829167   PMID:22658674   PMID:22681889   PMID:23828042   PMID:24726324   PMID:25225333   PMID:26255671   PMID:28755400   PMID:28821679   PMID:35659652  


Genomics

Comparative Map Data
Upf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,110,531 - 19,131,327 (+)NCBIGRCr8
mRatBN7.21619,076,594 - 19,097,365 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,076,322 - 19,096,568 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01620,824,888 - 20,845,632 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,824,864 - 20,845,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,677,403 - 20,698,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1619,266,888 - 19,287,629 (+)NCBICelera
Cytogenetic Map16p14NCBI
UPF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,831,959 - 18,868,230 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,831,959 - 18,868,230 (+)EnsemblGRCh38hg38GRCh38
GRCh371918,942,768 - 18,979,039 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,803,744 - 18,840,039 (+)NCBINCBI36Build 36hg18NCBI36
Build 341918,803,787 - 18,840,038NCBI
Celera1918,847,541 - 18,883,840 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,507,089 - 18,543,390 (+)NCBIHuRef
CHM1_11918,942,555 - 18,978,848 (+)NCBICHM1_1
T2T-CHM13v2.01918,967,570 - 19,003,847 (+)NCBIT2T-CHM13v2.0
Upf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,784,143 - 70,806,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,784,175 - 70,805,928 (-)EnsemblGRCm39 Ensembl
GRCm38870,331,493 - 70,353,423 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,331,525 - 70,353,278 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,855,421 - 72,877,172 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,260,514 - 73,282,268 (-)NCBIMGSCv36mm8
Celera872,887,999 - 72,909,735 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Upf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,798,336 - 2,913,176 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,798,336 - 2,814,063 (-)NCBIChiLan1.0ChiLan1.0
UPF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,693,196 - 23,729,529 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,699,421 - 22,735,743 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,269,878 - 18,306,199 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,293,020 - 19,315,295 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,292,725 - 19,313,224 (+)Ensemblpanpan1.1panPan2
UPF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,234,411 - 44,271,129 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,236,264 - 44,270,916 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,149,222 - 44,185,842 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,720,750 - 44,757,369 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,720,766 - 44,757,522 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,958,032 - 43,994,646 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,368,223 - 44,404,830 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,643,707 - 44,680,326 (-)NCBIUU_Cfam_GSD_1.0
Upf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,920,305 - 202,956,549 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,468,116 - 2,505,688 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,469,444 - 2,505,688 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UPF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,975,023 - 59,013,495 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,975,013 - 59,013,546 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,558,438 - 58,561,969 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UPF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,291,189 - 17,328,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,291,175 - 17,330,193 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660741,996,616 - 2,034,083 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Upf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,910,315 - 1,933,655 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,909,995 - 1,935,370 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Upf1
57 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:59
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000027268
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat

Markers in Region
Rent1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,084,910 - 19,085,883 (+)MAPPERmRatBN7.2
Rnor_6.01620,833,183 - 20,834,155NCBIRnor6.0
Rnor_5.01620,685,725 - 20,686,697UniSTSRnor5.0
Celera1619,275,180 - 19,276,152UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000027268   ⟹   ENSRNOP00000027268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1620,825,044 - 20,845,213 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1620,839,466 - 20,839,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092293   ⟹   ENSRNOP00000075829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1620,824,864 - 20,845,243 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092446   ⟹   ENSRNOP00000075905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1619,076,322 - 19,096,568 (+)Ensembl
Rnor_6.0 Ensembl1620,824,877 - 20,844,844 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1620,834,492 - 20,836,999 (+)Ensembl
RefSeq Acc Id: NM_001427359   ⟹   NP_001414288
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,110,538 - 19,131,327 (+)NCBI
RefSeq Acc Id: XM_063275730   ⟹   XP_063131800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,110,561 - 19,131,325 (+)NCBI
RefSeq Acc Id: XM_063275731   ⟹   XP_063131801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,110,531 - 19,131,325 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001414288 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131800 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131801 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL90680 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075905.1
Ensembl Acc Id: ENSRNOP00000075829   ⟸   ENSRNOT00000092293
Ensembl Acc Id: ENSRNOP00000075905   ⟸   ENSRNOT00000092446
Ensembl Acc Id: ENSRNOP00000027268   ⟸   ENSRNOT00000027268
RefSeq Acc Id: XP_063131801   ⟸   XM_063275731
- Peptide Label: isoform X2
- UniProtKB: A6KA57 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414288   ⟸   NM_001427359
- UniProtKB: A6KA57 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131800   ⟸   XM_063275730
- Peptide Label: isoform X1
- UniProtKB: A0A0U1RS25 (UniProtKB/TrEMBL)
Protein Domains
UPF1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0U1RS25-F1-model_v2 AlphaFold A0A0U1RS25 1-1124 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700038
Promoter ID:EPDNEW_R10558
Type:initiation region
Name:Upf1_1
Description:UPF1, RNA helicase and ATPase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,824,847 - 20,824,907EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589127 AgrOrtholog
BioCyc Gene G2FUF-11773 BioCyc
Ensembl Genes ENSRNOG00000020134 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000092446.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.30.230 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  6.10.140.1240 UniProtKB/TrEMBL
InterPro DNA2/NAM7-like UniProtKB/TrEMBL
  DNA2/NAM7_AAA_11 UniProtKB/TrEMBL
  DNA2/NAM7_like_AAA_12 UniProtKB/TrEMBL
  DUF5599 UniProtKB/TrEMBL
  Helicase/UvrB_N UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA-helicase_UPF1_UPF2-interct UniProtKB/TrEMBL
  SF1_C_Upf1 UniProtKB/TrEMBL
NCBI Gene 684558 ENTREZGENE
PANTHER PTHR10887 UniProtKB/TrEMBL
  REGULATOR OF NONSENSE TRANSCRIPTS 1 UniProtKB/TrEMBL
Pfam AAA_11 UniProtKB/TrEMBL
  AAA_12 UniProtKB/TrEMBL
  DUF5599 UniProtKB/TrEMBL
  ResIII UniProtKB/TrEMBL
  UPF1_Zn_bind UniProtKB/TrEMBL
PhenoGen Upf1 PhenoGen
PROSITE UPF1_CH_RICH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020134 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0U1RS25 ENTREZGENE, UniProtKB/TrEMBL
  A6KA57 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Upf1  UPF1, RNA helicase and ATPase  Upf1  UPF1 regulator of nonsense transcripts homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-13 Upf1  UPF1 regulator of nonsense transcripts homolog (yeast)  LOC684558  similar to regulator of nonsense transcripts 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-13 Upf1  UPF1 regulator of nonsense transcripts homolog (yeast)  Upf1  UPF1 regulator of nonsense transcripts homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC684558  similar to regulator of nonsense transcripts 1      Symbol and Name status set to provisional 70820 PROVISIONAL