Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736367
Species: Homo sapiens
RGD Object: Gene
Symbol: PDX1
Name: pancreatic and duodenal homeobox 1
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDX1multiple interactionsEXP 6480464CTD[wortmannin co-treated with INS protein] inhibits the reaction [Glucose affects the localization of PDX1 protein]; wortmannin inhibits the reaction [Glucose affects the localization of PDX1 protein]; wortmannin inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of PDX1 protein]PMID:11574405 PMID:9873045
PDX1multiple interactionsISOPdx1 (Mus musculus)6480464CTDwortmannin inhibits the reaction [Glucose affects the localization of PDX1 protein]PMID:11574405
Go Back to source page   Continue to Ontology report