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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733440
Species: Homo sapiens
RGD Object: Gene
Symbol: BECN1
Name: beclin 1
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BECN1multiple interactionsEXP 6480464CTDwortmannin promotes the reaction [Ethanol results in increased degradation of BECN1 protein]PMID:21410490
BECN1decreases expressionISOBecn1 (Rattus norvegicus)6480464CTDwortmannin results in decreased expression of BECN1 proteinPMID:23604964
BECN1multiple interactionsISOBecn1 (Rattus norvegicus)6480464CTDwortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein]PMID:23604964
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