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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315401
Species: Homo sapiens
RGD Object: Gene
Symbol: CHUK
Name: component of inhibitor of nuclear factor kappa B kinase complex
Acc ID: CHEBI:42106
Term: L-1,4-dithiothreitol
Definition: A 1,4-dithiothreitol that has formula C4H10O2S2.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CHUKmultiple interactionsISOChuk (Mus musculus)6480464CTDDithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of CHUK protein]; Dithiothreitol inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of CHUK protein]]PMID:17067557
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