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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732174
Species: Homo sapiens
RGD Object: Gene
Symbol: BCHE
Name: butyrylcholinesterase
Acc ID: CHEBI:35016
Term: Tiapamil
Definition: An organic amino compound that has formula C26H37NO8S2.
Chemical ID: MESH:D013976
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCHEaffects bindingEXP 6480464CTDTiapamil Hydrochloride binds to BCHE proteinPMID:16193528
BCHEmultiple interactionsEXP 6480464CTDTiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]PMID:16036766 PMID:16193528
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