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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3602
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rps6
Name: ribosomal protein S6
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6increases phosphorylationISORps6 (Mus musculus)6480464CTDDextran Sulfate results in increased phosphorylation of RPS6 proteinPMID:31676321
Rps6multiple interactionsISORps6 (Mus musculus)6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]]; [Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of RPS6 protein; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]PMID:19931517 PMID:31676321
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