Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735659
Species: Homo sapiens
RGD Object: Gene
Symbol: SNAI2
Name: snail family transcriptional repressor 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SNAI2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SNAI2 mRNAPMID:29718440
SNAI2increases expressionEXP 6480464CTDbisphenol A results in increased expression of SNAI2 mRNA; bisphenol A results in increased expression of SNAI2 proteinPMID:25690688 PMID:28844962 PMID:29275510
SNAI2multiple interactionsEXP 6480464CTD3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of SNAI2 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; plerixafor inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]PMID:25690688 PMID:28844962
SNAI2decreases expressionISOSnai2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of SNAI2 mRNAPMID:25181051 PMID:30816183 PMID:32528016
SNAI2increases expressionISOSnai2 (Mus musculus)6480464CTDbisphenol A results in increased expression of SNAI2 mRNAPMID:30951980 PMID:35479511
Go Back to source page   Continue to Ontology report