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Gene: SNAI2 (snail family transcriptional repressor 2) Homo sapiens
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Symbol: SNAI2
Name: snail family transcriptional repressor 2
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and E-box binding activity. Involved in several processes, including mesenchymal cell differentiation; negative regulation of cellular biosynthetic process; and negative regulation of signal transduction. Localizes to nuclear chromatin. Implicated in Waardenburg syndrome type 2D and piebaldism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC10182; neural crest transcription factor SLUG; SLUG; slug (chicken homolog), zinc finger protein; SLUGH; SLUGH1; snail 2; snail family zinc finger 2; snail homolog 2; SNAIL2; WS2D; zinc finger protein SNAI2
Orthologs:
Mus musculus (house mouse) : Snai2 (snail family zinc finger 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snai2 (snail family transcriptional repressor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snai2 (snail family transcriptional repressor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SNAI2 (snail family transcriptional repressor 2)
Canis lupus familiaris (dog) : SNAI2 (snail family transcriptional repressor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snai2 (snail family transcriptional repressor 2)
Sus scrofa (pig) : SNAI2 (snail family transcriptional repressor 2)
Chlorocebus sabaeus (African green monkey) : SNAI2 (snail family transcriptional repressor 2)
Heterocephalus glaber (naked mole-rat) : Snai2 (snail family transcriptional repressor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl848,917,598 - 48,921,740 (-)EnsemblGRCh38hg38GRCh38
GRCh38848,917,598 - 48,921,429 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37849,830,236 - 49,833,999 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36849,992,789 - 49,996,541 (-)NCBINCBI36hg18NCBI36
Build 34849,992,795 - 49,996,541NCBI
Celera845,817,447 - 45,821,199 (-)NCBI
Cytogenetic Map8q11.21NCBI
HuRef845,294,292 - 45,298,055 (-)NCBIHuRef
CHM1_1849,882,550 - 49,886,313 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SNAI2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735659
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.