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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ctcf
Name: CCCTC-binding factor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctcfincreases expressionEXP 6480464CTDbisphenol A results in increased expression of CTCF mRNAPMID:25181051
Ctcfaffects methylationISOCtcf (Mus musculus)6480464CTDbisphenol A affects the methylation of CTCF promoterPMID:27334623
Ctcfdecreases expressionISOCtcf (Mus musculus)6480464CTDbisphenol A results in decreased expression of CTCF mRNAPMID:33221593
Ctcfmultiple interactionsISOCTCF (Homo sapiens)6480464CTD[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CTCF proteinPMID:31629898
Ctcfmultiple interactionsISOCtcf (Mus musculus)6480464CTDbisphenol A promotes the reaction [CTCF protein binds to FTO intron]PMID:36469784
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