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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359429
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fggy
Name: FGGY carbohydrate kinase domain containing
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fggyaffects expressionEXP 6480464CTDbisphenol A affects the expression of FGGY mRNAPMID:25181051
Fggyincreases expressionEXP 6480464CTDbisphenol A results in increased expression of FGGY mRNAPMID:32145629
Fggyincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of FGGY genePMID:28505145
Fggydecreases methylationISOFggy (Mus musculus)6480464CTDbisphenol A results in decreased methylation of FGGY promoterPMID:29220483
Fggydecreases methylationISOFGGY (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of FGGY genePMID:31601247
Fggyincreases expressionISOFggy (Mus musculus)6480464CTDbisphenol A results in increased expression of FGGY mRNAPMID:25594700 PMID:29220483
Fggyincreases expressionISOFGGY (Homo sapiens)6480464CTDbisphenol A results in increased expression of FGGY mRNAPMID:27685785
Fggymultiple interactionsISOFGGY (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of FGGY genePMID:31601247
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