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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349272
Species: Homo sapiens
RGD Object: Gene
Symbol: PON1
Name: paraoxonase 1
Acc ID: CHEBI:33135
Term: pyrrolidine
Definition: A cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family.
Chemical ID: MESH:C032519
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PON1multiple interactionsEXP 6480464CTD[pyrrolidine analog binds to Palladium binds to Diclofenac] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Palladium binds to Mefenamic Acid] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Platinum binds to Diclofenac] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Platinum binds to Mefenamic Acid] which results in decreased activity of PON1 proteinPMID:29512227
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