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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10438
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:32692
Term: 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one
Definition: A nitrosamine that has formula C10H13N3O2.
Chemical ID: MESH:C016583
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2increases activityISOCYP1A2 (Homo sapiens)6480464CTDCYP1A2 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanonePMID:15728263
Cyp1a2multiple interactionsISOCYP1A2 (Homo sapiens)6480464CTDCYP1A2 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanonePMID:11774366
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