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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733524
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp1r14a
Name: protein phosphatase 1, regulatory inhibitor subunit 14A
Acc ID: CHEBI:31653
Term: glafenine
Definition: A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.
Chemical ID: MESH:D005897
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp1r14aincreases expressionISOPpp1r14a (Rattus norvegicus)6480464CTDGlafenine results in increased expression of PPP1R14A mRNAPMID:24136188
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