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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621421
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp9a
Name: ATPase phospholipid transporting 9A (putative)
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp9aaffects methylationISOATP9A (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of ATP9A 3' UTR; Benzo(a)pyrene affects the methylation of ATP9A promoterPMID:27901495
Atp9adecreases expressionISOATP9A (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of ATP9A mRNAPMID:20106945 PMID:21632981 PMID:26238291
Atp9adecreases expressionISOAtp9a (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of ATP9A mRNAPMID:19770486 PMID:22228805
Atp9adecreases methylationISOAtp9a (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of ATP9A intronPMID:27901495
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