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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316414
Species: Mus musculus
RGD Object: Gene
Symbol: Ryr1
Name: ryanodine receptor 1, skeletal muscle
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ryr1multiple interactionsEXP 6480464CTD[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of RYR1 mRNAPMID:34876320
Ryr1decreases expressionISORYR1 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of RYR1 mRNAPMID:28713220 PMID:34032870
Ryr1increases expressionISORYR1 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of RYR1 mRNAPMID:33241020
Ryr1multiple interactionsISORYR1 (Homo sapiens)6480464CTDoxymatrine promotes the reaction [sodium arsenite results in increased expression of RYR1 mRNA]PMID:33241020
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