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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552032
Species: Mus musculus
RGD Object: Gene
Symbol: Pfkfb4
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pfkfb4decreases expressionISOPfkfb4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PFKFB4 mRNAPMID:21724226 PMID:32109520
Pfkfb4increases expressionISOPfkfb4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PFKFB4 mRNAPMID:33387578
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