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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551127
Species: Mus musculus
RGD Object: Gene
Symbol: Tfap2c
Name: transcription factor AP-2, gamma
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tfap2caffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of TFAP2C mRNAPMID:14708085 PMID:16962184
Tfap2cincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of TFAP2C mRNAPMID:17035482 PMID:24058054
Tfap2cmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TFAP2C mRNA; SRC protein promotes the reaction [Tetrachlorodibenzodioxin affects the expression of TFAP2C mRNA]PMID:14708085 PMID:17942748
Tfap2cincreases expressionISOTfap2c (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TFAP2C mRNAPMID:34747641
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