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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352480
Species: Homo sapiens
RGD Object: Gene
Symbol: NDUFA4
Name: NDUFA4 mitochondrial complex associated
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NDUFA4affects expressionISONdufa4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of NDUFA4 mRNAPMID:34747641
NDUFA4affects expressionISONdufa4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of NDUFA4 mRNAPMID:21570461
NDUFA4decreases expressionISONdufa4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of NDUFA4 mRNAPMID:33387578
NDUFA4increases expressionISONdufa4 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of NDUFA4 mRNAPMID:15034205 PMID:20399798
NDUFA4multiple interactionsISONdufa4 (Mus musculus)6480464CTDAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NDUFA4 mRNA]PMID:15034205
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