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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317132
Species: Mus musculus
RGD Object: Gene
Symbol: Sphk2
Name: sphingosine kinase 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sphk2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SPHK2 mRNAPMID:21570461
Sphk2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SPHK2 mRNAPMID:28213091
Sphk2decreases expressionISOSphk2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SPHK2 mRNAPMID:21215274
Sphk2increases expressionISOSphk2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SPHK2 mRNAPMID:19520675
Sphk2multiple interactionsISOSphk2 (Rattus norvegicus)6480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of SPHK2 mRNA]PMID:21215274
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