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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314497
Species: Homo sapiens
RGD Object: Gene
Symbol: H4C8
Name: H4 clustered histone 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H4C8increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of H4C8 mRNAPMID:20106945 PMID:21632981
H4C8affects expressionISOH4c12 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of H4C12 mRNA; Tetrachlorodibenzodioxin affects the expression of H4C8 mRNAPMID:21570461 PMID:24680724 PMID:26377647
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