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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321417
Species: Mus musculus
RGD Object: Gene
Symbol: Map3k14
Name: mitogen-activated protein kinase kinase kinase 14
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k14multiple interactionsISOMap3k14 (Rattus norvegicus)6480464CTDMAP3K14 protein affects the reaction [Manganese promotes the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]PMID:15010209
Map3k14multiple interactionsISOMAP3K14 (Homo sapiens)6480464CTD[NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of MAP3K14 mRNAPMID:35877022
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