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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10092
Species: Mus musculus
RGD Object: Gene
Symbol: Adora2a
Name: adenosine A2a receptor
Acc ID: CHEBI:16335
Term: adenosine
Definition: A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.
Chemical ID: MESH:D000241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adora2aaffects bindingISOADORA2A (Homo sapiens)6480464CTDAdenosine binds to ADORA2A proteinPMID:18404447
Adora2amultiple interactionsISOADORA2A (Homo sapiens)6480464CTDAdenosine analog binds to and results in decreased activity of ADORA2A protein; Adenosine promotes the reaction [Lipopolysaccharides results in increased expression of ADORA2A mRNA]PMID:18404447 PMID:20067761
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