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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735270
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP7B1
Name: cytochrome P450 family 7 subfamily B member 1
Acc ID: CHEBI:16113
Term: cholesterol
Definition: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Chemical ID: MESH:D002784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP7B1increases activityISOCyp7b1 (Rattus norvegicus)6480464CTDCholesterol results in increased activity of CYP7B1 proteinPMID:12029625
CYP7B1increases expressionISOCyp7b1 (Rattus norvegicus)6480464CTDCholesterol results in increased expression of CYP7B1 mRNAPMID:12029625
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