Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69097
Species: Homo sapiens
RGD Object: Gene
Symbol: LHB
Name: luteinizing hormone subunit beta
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LHBmultiple interactionsISOLhb (Mus musculus)6480464CTDTretinoin inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Tretinoin inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]]PMID:22285649
LHBmultiple interactionsISOLhb (Rattus norvegicus)6480464CTDTretinoin inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]PMID:21964460
Go Back to source page   Continue to Ontology report