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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316150
Species: Mus musculus
RGD Object: Gene
Symbol: Zfp42
Name: zinc finger protein 42
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zfp42decreases expressionEXP 6480464CTDTretinoin results in decreased expression of ZFP42 mRNAPMID:16604517 PMID:22466603
Zfp42multiple interactionsEXP 6480464CTDEHMT2 protein promotes the reaction [Tretinoin promotes the reaction [CBX1 protein binds to ZFP42 promoter]]; Tretinoin promotes the reaction [[H3F4 protein modified form binds to CBX1 protein] which binds to ZFP42 promoter]PMID:16415856
Zfp42decreases expressionISOZFP42 (Homo sapiens)6480464CTDTretinoin results in decreased expression of ZFP42 mRNAPMID:21934132
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