Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | multiple interactions | EXP | | 6480464 | Tubocurarine inhibits the reaction [Nicotine results in increased expression of ZFP42 mRNA] | CTD | PMID:15749260 | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of ZFP42 mRNA | CTD | PMID:15749260 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZFP42 mRNA | CTD | PMID:17942748 | 17beta-estradiol 3-benzoate | decreases expression | ISO | Zfp42 (Rattus norvegicus) | 6480464 | estradiol 3-benzoate results in decreased expression of ZFP42 mRNA | CTD | PMID:32741896 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZFP42 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFP42 mRNA | CTD | PMID:21570461 | 5-fluorouracil | decreases expression | EXP | | 6480464 | Fluorouracil results in decreased expression of ZFP42 protein | CTD | PMID:21296659 | acetic acid | increases expression | EXP | | 6480464 | Acetic Acid results in increased expression of ZFP42 protein | CTD | PMID:21296659 | all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | EHMT2 protein promotes the reaction [Tretinoin promotes the reaction [CBX1 protein binds to ZFP42 promoter]] and Tretinoin promotes the reaction [[H3F4 protein modified form binds to CBX1 protein] which binds to ZFP42 promoter] | CTD | PMID:16415856 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of ZFP42 mRNA | CTD | PMID:16604517 and PMID:22466603 | all-trans-retinoic acid | decreases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ZFP42 mRNA | CTD | PMID:21934132 | antirheumatic drug | decreases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ZFP42 mRNA | CTD | PMID:24449571 | arsenite(3-) | increases methylation | ISO | ZFP42 (Homo sapiens) | 6480464 | arsenite results in increased methylation of ZFP42 promoter | CTD | PMID:23974009 | arsenite(3-) | decreases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | arsenite results in decreased expression of ZFP42 mRNA | CTD | PMID:23974009 | arsenous acid | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of ZFP42 mRNA | CTD | PMID:29767511 | belinostat | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | belinostat results in increased expression of ZFP42 mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases mutagenesis | ISO | ZFP42 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of ZFP42 gene | CTD | PMID:25435355 | benzo[a]pyrene | affects methylation | ISO | ZFP42 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ZFP42 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | ZFP42 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ZFP42 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZFP42 mRNA | CTD | PMID:31288075 | bromochloroacetic acid | increases expression | EXP | | 6480464 | bromochloroacetic acid results in increased expression of ZFP42 protein | CTD | PMID:21296659 | diarsenic trioxide | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of ZFP42 mRNA | CTD | PMID:29767511 | dioxygen | multiple interactions | EXP | | 6480464 | Oxygen deficiency promotes the reaction [LIF protein affects the reaction ZFP42 mRNA] | CTD | PMID:26723917 | dorsomorphin | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | entinostat results in increased expression of ZFP42 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA | CTD | PMID:27188386 | indometacin | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Indomethacin results in increased expression of ZFP42 mRNA | CTD | PMID:24737281 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of ZFP42 mRNA | CTD | PMID:31715224 | malathion | decreases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Malathion results in decreased expression of ZFP42 mRNA | CTD | PMID:37047231 | methylmercury chloride | decreases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ZFP42 mRNA | CTD | PMID:23179753 and PMID:27188386 | methylmercury chloride | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of ZFP42 mRNA | CTD | PMID:28001369 | monosodium L-glutamate | increases expression | EXP | | 6480464 | Sodium Glutamate results in increased expression of ZFP42 mRNA | CTD | PMID:22078008 | nicotine | multiple interactions | EXP | | 6480464 | Tubocurarine inhibits the reaction [Nicotine results in increased expression of ZFP42 mRNA] | CTD | PMID:15749260 | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of ZFP42 mRNA | CTD | PMID:15749260 | Nonylphenol | increases expression | EXP | | 6480464 | nonylphenol results in increased expression of ZFP42 mRNA | CTD | PMID:31288075 | panobinostat | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | panobinostat results in increased expression of ZFP42 mRNA | CTD | PMID:26272509 | paracetamol | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ZFP42 mRNA | CTD | PMID:26690555 | PCB138 | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | SB 431542 | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | serpentine asbestos | decreases methylation | ISO | ZFP42 (Homo sapiens) | 6480464 | Asbestos and Serpentine results in decreased methylation of ZFP42 5' UTR | CTD | PMID:29523930 | sodium arsenite | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ZFP42 mRNA | CTD | PMID:34032870 | trichostatin A | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ZFP42 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA | CTD | PMID:27188386 | tubocurarine | multiple interactions | EXP | | 6480464 | Tubocurarine inhibits the reaction [Nicotine results in increased expression of ZFP42 mRNA] | CTD | PMID:15749260 | valproic acid | affects expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ZFP42 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ZFP42 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA | CTD | PMID:27188386 | vorinostat | multiple interactions | ISO | ZFP42 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA | CTD | PMID:27188386 | vorinostat | increases expression | ISO | ZFP42 (Homo sapiens) | 6480464 | vorinostat results in increased expression of ZFP42 mRNA | CTD | PMID:26272509 | |