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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350163
Species: Homo sapiens
RGD Object: Gene
Symbol: PPP1R12A
Name: protein phosphatase 1 regulatory subunit 12A
Acc ID: CHEBI:143170
Term: aldrithiol
Definition: A member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols.
Chemical ID: MESH:C001105
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPP1R12Aincreases phosphorylationISOPpp1r12a (Rattus norvegicus)6480464CTD2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A proteinPMID:25449040
PPP1R12Amultiple interactionsISOPpp1r12a (Rattus norvegicus)6480464CTDpolydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A protein]PMID:25449040
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