GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSD11B2 | decreases activity | EXP | | 6480464 | CTD | tributyltin results in decreased activity of HSD11B2 protein | PMID:16184081 PMID:22796344 | HSD11B2 | increases expression | EXP | | 6480464 | CTD | tributyltin results in increased expression of HSD11B2 mRNA | PMID:31927052 | HSD11B2 | multiple interactions | EXP | | 6480464 | CTD | Cycloheximide promotes the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Glycyrrhetinic Acid inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein]; LG 100754 inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [tributyltin results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; RXRA protein affects the reaction [tributyltin results in increased expression of HSD11B2 protein]; tributyltin results in increased expression of and results in increased activity of HSD11B2 protein | PMID:31927052 | | ||||||||||||||||||||||
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