Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737462
Species: Homo sapiens
RGD Object: Gene
Symbol: TXN2
Name: thioredoxin 2
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TXN2increases oxidationEXP 6480464CTDHydrogen Peroxide results in increased oxidation of TXN2 proteinPMID:16797630 PMID:17018646 PMID:26975474
TXN2increases oxidationISOTxn2 (Rattus norvegicus)6480464CTDHydrogen Peroxide results in increased oxidation of TXN2 proteinPMID:26975474
TXN2increases oxidationISOTxn2 (Mus musculus)6480464CTDHydrogen Peroxide results in increased oxidation of TXN2 proteinPMID:22495766
TXN2multiple interactionsISOTxn2 (Mus musculus)6480464CTD[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] inhibits the reaction [Hydrogen Peroxide results in increased oxidation of TXN2 protein]; [Sodium Azide co-treated with Hydrogen Peroxide] affects the expression of TXN2 mRNAPMID:15133893 PMID:22495766
Go Back to source page   Continue to Ontology report