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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737225
Species: Homo sapiens
RGD Object: Gene
Symbol: COL3A1
Name: collagen type III alpha 1 chain
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
COL3A1multiple interactionsEXP 6480464CTD[Chelating Agents binds to Copper] which results in decreased expression of COL3A1 mRNA; [Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNAPMID:24690739 PMID:30911355 PMID:31162603
COL3A1decreases expressionISOCol3a1 (Rattus norvegicus)6480464CTDCopper results in decreased expression of COL3A1 mRNAPMID:30556269
COL3A1increases expressionISOCol3a1 (Rattus norvegicus)6480464CTDCopper deficiency results in increased expression of COL3A1 mRNAPMID:17418555
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