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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737222
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Acc ID: CHEBI:9464
Term: testosterone enanthate
Definition: An enanthate ester that has formula C26H40O3.
Chemical ID: MESH:C004648
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp17a1decreases expressionISOCyp17a1 (Rattus norvegicus)6480464CTDtestosterone enanthate results in decreased expression of CYP17A1 mRNAPMID:21427060 PMID:25603467
Cyp17a1multiple interactionsISOCYP17A1 (Homo sapiens)6480464CTD[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP17A1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CYP17A1 mRNAPMID:18160741
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