Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736638
Species: Homo sapiens
RGD Object: Gene
Symbol: GLP1R
Name: glucagon like peptide 1 receptor
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GLP1Rmultiple interactionsISOGlp1r (Mus musculus)6480464CTD[GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]PMID:18669601
GLP1Rmultiple interactionsISOGlp1r (Rattus norvegicus)6480464CTD[GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; [Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein; exenatide inhibits the reaction [[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein]PMID:18669601 PMID:22925809
Go Back to source page   Continue to Ontology report