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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736515
Species: Homo sapiens
RGD Object: Gene
Symbol: SOD3
Name: superoxide dismutase 3
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD3increases expressionEXP 6480464CTDParaquat results in increased expression of SOD3 mRNAPMID:22996356
SOD3multiple interactionsEXP 6480464CTD[Quercetin co-treated with Paraquat] results in increased expression of SOD3 mRNAPMID:22996356
SOD3decreases expressionISOSod3 (Mus musculus)6480464CTDParaquat results in decreased expression of SOD3 mRNAPMID:17215068 PMID:26108578
SOD3increases expressionISOSod3 (Mus musculus)6480464CTDParaquat results in increased expression of SOD3 mRNAPMID:12732627 PMID:21688324
SOD3multiple interactionsISOSod3 (Mus musculus)6480464CTDAPOD protein affects the reaction [Paraquat results in increased expression of SOD3 mRNA]PMID:21688324
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