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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736277
Species: Mus musculus
RGD Object: Gene
Symbol: Uchl1
Name: ubiquitin carboxy-terminal hydrolase L1
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Uchl1increases expressionEXP 6480464CTDDoxorubicin results in increased expression of UCHL1 mRNAPMID:36227756
Uchl1affects expressionISOUCHL1 (Homo sapiens)6480464CTDDoxorubicin affects the expression of UCHL1 mRNA; Doxorubicin affects the expression of UCHL1 proteinPMID:29385562 PMID:29803840
Uchl1decreases expressionISOUchl1 (Rattus norvegicus)6480464CTDDoxorubicin results in decreased expression of UCHL1 mRNAPMID:32289291
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