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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735942
Species: Mus musculus
RGD Object: Gene
Symbol: Crem
Name: cAMP responsive element modulator
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cremdecreases expressionISOCrem (Rattus norvegicus)6480464CTDEstradiol results in decreased expression of CREM mRNAPMID:32145629
Cremdecreases expressionISOCREM (Homo sapiens)6480464CTDEstradiol results in decreased expression of CREM mRNAPMID:23019147
Cremincreases expressionISOCREM (Homo sapiens)6480464CTDEstradiol results in increased expression of CREM mRNAPMID:20106945
Cremmultiple interactionsISOCREM (Homo sapiens)6480464CTD[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CREM mRNA; [Estradiol co-treated with EGF protein] results in increased expression of CREM mRNAPMID:20823114 PMID:24758408
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